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  • 小鼠抗MSL2單克隆抗體

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW7338
    • 應(yīng)用 : 僅限于科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存:40
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中文名稱(chēng):小鼠抗MSL2單克隆抗體

英文名稱(chēng): Anti-MSL2 mouse monoclonal antibody

別      名: MSL complex subunit 2; MSL-2; MSL2L1; RNF184

相關(guān)類(lèi)別: 一抗

儲(chǔ)      存: 冷凍(-20℃)

宿      主: Mouse

抗      原: MSL2

反應(yīng)種屬: Human

標(biāo)  記 物: Unconjugate

克隆類(lèi)型: mouse monoclonal


技術(shù)規(guī)格

Background:

Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at lysine 16 which is implicated in the formation of higher-order chromatin structure. Acts as an E3 ubiquitin ligase that promotes monoubiquitination of histone H2B at 'Lys-35' (H2BK34Ub), but not that of H2A. This activity is greatly enhanced by heterodimerization with MSL1. H2B ubiquitination in turn stimulates histine H3 methylation at 'Lys-4' (H3K4me) and 'Lys-79' (H3K79me) and leads to gene activation, including that of HOXA9 and MEIS1.

Applications:

WB

Name of antibody:

MSL2

Immunogen:

Fusion protein of human MSL2

Full name:

MSL complex subunit 2

Synonyms:

MSL-2; MSL2L1; RNF184

SwissProt:

Q9HCI7

WB Predicted band size:

63 KD

WB Positive control:

Hela cell lysate

WB Recommended dilution:

500-2000