反應(yīng)種屬: Human Mouse Rat
克隆類型: Unconjugate
技術(shù)規(guī)格
Background:
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1.
Applications:
WB
Name of antibody:
HDAC3(Phospho-Ser424)
Immunogen:
Peptide sequence around phosphorylation site of Serine 424 (K-E-S(p)-D-V) derived from Human HDAC3
Full name:
histone deacetylase 3
Synonyms:
HD3; RPD3; RPD3-2
SwissProt:
O15379
WB Predicted band size:
49 kDa
WB Positive control:
Mouse brain tissue lysates
WB Recommended dilution:
500-1000