克隆類型: rabbit polyclonal
技術(shù)規(guī)格
Background: |
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. |
Applications: |
ELISA, IHC |
Name of antibody: |
HDAC8 |
Immunogen: |
Fusion protein of human HDAC8 |
Full name: |
histone deacetylase 8 |
Synonyms: |
HD8; WTS; RPD3; CDA07; CDLS5; MRXS6; HDACL1 |
SwissProt: |
Q9BY41 |
ELISA Recommended dilution: |
2000-5000 |
IHC positive control: |
Human brain and human esophagus cancer |
IHC Recommend dilution: |
50-200 |