購物車
幫助
021-54845833/15800441009
標(biāo) 記 物： Unconjugate
技術(shù)規(guī)格
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Background: |
Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
HGF |
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Immunogen: |
Fusion protein of human HGF |
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Full name: |
hepatocyte growth factor (hepapoietin A; scatter factor) |
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Synonyms： |
SF; HGFB; HPTA; F-TCF; DFNB39 |
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SwissProt: |
P14210 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human thyroid cancer and Human gastric cancer |
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IHC Recommend dilution: |
50-200 |
