兔抗HSD17B1多克隆抗體

Background:

Hydroxysteroid (17-beta) dehydrogenase 1 catalyzes the final step in the formation of estradiol and testosterone from estrone and androstenedione, respectively. Ovarian granulosa cells and breast tissue both express HSD17B1. Other tissues that express HSD17B1 include testis, placenta, uterus, prostate and adipose tissue. HSD17B1 functions as a homodimer and prefers NADP(H) over NAD(H) for oxidation and reduction. The gene encoding human HSD17B1 maps to chromosome 17q12-q21. The importance of HSD17B1 to estradiol production suggests the specific inhibition of HSD17B1 may aid in breast cancer therapy.

Applications:

ELISA, WB, IHC

Name of antibody:

HSD17B1

Immunogen:

Synthetic peptide of human HSD17B1

Full name:

hydroxysteroid (17-beta) dehydrogenase 1

Synonyms：

HSD17; EDHB17; EDH17B2; SDR28C1

SwissProt:

P14061

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human brain and Human gastric cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

35 kDa

WB Positive control:

Human placenta tissue

WB Recommended dilution:

500-2000