兔抗ITGB1BP1多克隆抗體

Background:

The cytoplasmic domains of integrins are essential for cell adhesion. The protein encoded by this gene binds to the beta1 integrin cytoplasmic domain. The interaction between this protein and beta1 integrin is highly specific. Two isoforms of this protein are derived from alternatively spliced transcripts. The shorter form of this protein does not interact with the beta1 integrin cytoplasmic domain. The longer form is a phosphoprotein and the extent of its phosphorylation is regulated by the cell-matrix interaction, suggesting an important role of this protein during integrin-dependent cell adhesion. Several transcript variants, some protein-coding and some non-protein coding, have been found for this gene.

Applications:

ELISA, IHC

Name of antibody:

ITGB1BP1

Immunogen:

Fusion protein of human ITGB1BP1

Full name:

integrin subunit beta 1 binding protein 1

Synonyms:

ICAP1; ICAP1A; ICAP1B; ICAP-1A; ICAP-1B; ICAP-1alpha

SwissProt:

O14713

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human thyroid cancer and Human esophagus cancer

IHC Recommend dilution:

50-200