兔抗IL10RA多克隆抗體

Background:

The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.

Applications:

ELISA, IHC

Name of antibody:

IL10RA

Immunogen:

Fusion protein of human IL10RA

Full name:

Interleukin-10 receptor subunit alpha

Synonyms：

CD210, IL10R, CD210a, CDW210A, HIL-10R, IL-10R1

SwissProt:

Q13651

ELISA Recommended dilution:

1000-10000

IHC positive control:

Human lung cancer and human tonsil

IHC Recommend dilution:

25-100