購物車
幫助
021-54845833/15800441009
中文名稱：BMP4抗原（重組蛋白）
英文名稱：BMP4 Antigen (Recombinant Protein)
儲 存：冷凍（-20℃）
相關類別：抗原
|
Fusion protein corresponding to a region derived from 293-408 amino acids of human BMP4 |
技術規(guī)格
|
Full name: |
bone morphogenetic protein 4 |
|
Synonyms: |
ZYME; BMP2B; OFC11; BMP2B1; MCOPS6 |
|
Swissprot: |
P12644 |
|
Gene Accession: |
BC020546 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates heart development and adipogenesis. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers. |
