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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW999
    • 應(yīng)用 : 僅限于科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存:40
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中文名稱: 兔抗G6PC多克隆抗體

英文名稱: Anti-G6PC rabbit polyclonal antibody

別      名: glucose-6-phosphatase catalytic subunit; G6PT; GSD1; G6PC1; GSD1a; G6Pase

相關(guān)類別: 一抗

儲(chǔ)      存: 冷凍(-20℃)

宿      主: Rabbit

抗      原: G6PC

反應(yīng)種屬: Human, Mouse, Rat

標(biāo) 記  物: Unconjugate

克隆類型: rabbit polyclonal

技術(shù)規(guī)格


Background:

Glucose-6-phosphatase (G6Pase) is a multi-subunit integral membrane protein of the endoplasmic reticulum that is composed of a catalytic subunit and transporters for G6P, inorganic phosphate, and glucose. This gene (G6PC) is one of the three glucose-6-phosphatase catalytic-subunit-encoding genes in human: G6PC, G6PC2 and G6PC3. Glucose-6-phosphatase catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate and is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis. Mutations in this gene cause glycogen storage disease type I (GSD1). This disease, also known as von Gierke disease, is a metabolic disorder characterized by severe hypoglycemia associated with the accumulation of glycogen and fat in the liver and kidneys.

Applications:

ELISA, IHC

Name of antibody:

G6PC

Immunogen:

Synthetic peptide of human G6PC

Full name:

glucose-6-phosphatase catalytic subunit

Synonyms:

G6PT; GSD1; G6PC1; GSD1a; G6Pase

SwissProt:

P35575

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

50-300