歡迎來到上海通蔚！

021-54845833/15800441009

品質(zhì)保證 · 通蔚試劑

當(dāng)前位置: 首頁 > 科研產(chǎn)品 > 科研抗體 > 一抗 > 小鼠抗RBL1單克隆抗體

產(chǎn)品中心

  • 小鼠抗RBL1單克隆抗體

    規(guī)格：
    數(shù)量：

    購買數(shù)量

    價格：￥
    • 品牌 : 通蔚生物
    • 目錄號 : TW11844
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存：20
  • 商品詳情
  • 參考文獻(xiàn)
  • 說明書下載
  • 商品評論0
  • 相關(guān)產(chǎn)品
中文名稱： 小鼠抗RBL1單克隆抗體

英文名稱： Anti-RBL1 mouse monoclonal antibody

別     名： RB transcriptional corepressor like 1; PRB1; p107; CP107

相關(guān)類別： 一抗

儲     存： 冷凍（-20℃）

宿     主： Mouse

抗     原： RBL1

反應(yīng)種屬： Human

標(biāo) 記 物： Unconjugate

克隆類型： mouse monoclonal

技術(shù)規(guī)格

Background:

The protein encoded by this gene is similar in sequence and possibly function to the product of the retinoblastoma 1 (RB1) gene. The RB1 gene product is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 large T-antigen, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein. In addition, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. Due to the sequence and biochemical similarities with the RB1 protein, it is thought that the protein encoded by this gene may also be a tumor suppressor. Two transcript variants encoding different isoforms have been found for this gene.

Applications:

WB

Name of antibody:

RBL1

Immunogen:

Fusion protein of human RBL1

Full name:

RB transcriptional corepressor like 1

Synonyms:

PRB1; p107; CP107

SwissProt:

P28749

WB Predicted band size:

121 KD

WB Positive control:

293T cell lysate

WB Recommended dilution:

200-1000