小鼠抗RRM2單克隆抗體

Background:

This gene encodes one of two non-identical subunits for ribonucleotide reductase. This reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the encoded protein (M2) is regulated in a cell-cycle dependent fashion. Transcription from this gene can initiate from alternative promoters, which results in two isoforms that differ in the lengths of their N-termini. Related pseudogenes have been identified on chromosomes 1 and X.

Applications:

WB, IHC

Name of antibody:

RRM2

Immunogen:

Fusion protein of human RRM2

Full name:

ribonucleotide reductase regulatory subunit M2

Synonyms:

R2; RR2; RR2M

SwissProt:

P31350

IHC positive control:

Human kidney tissue and Human lung cancer; Human ovarian cancer and Human endometrial cancer

IHC Recommend dilution:

50-150

WB Predicted band size:

45 KD

WB Positive control:

HepG2, Hela, K562 and Jurkat cell lysates

WB Recommended dilution:

200-1000