技術規(guī)格
Background: |
This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 1. |
Applications: |
WB |
Name of antibody: |
SOD2 |
Immunogen: |
Fusion protein of human SOD2 |
Full name: |
superoxide dismutase 2 |
Synonyms: |
IPOB; IPO-B; MNSOD; MVCD6; Mn-SOD |
SwissProt: |
P04179 |
WB Predicted band size: |
25 kDa |
WB Positive control: |
Hela, THP-1, A549, Ramos and K562 cell lysates |
WB Recommended dilution: |
1000-5000 |