小鼠抗NRF1單克隆抗體

Background:

This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternative splicing results in multiple transcript variants. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for "nuclear factor (erythroid-derived 2)-like 1" which has an official symbol of NFE2L1.

Applications:

WB

Name of antibody:

NRF1

Immunogen:

Fusion protein of human NRF1

Full name:

nuclear respiratory factor 1

Synonyms:

ALPHA-PAL

SwissProt:

Q16656

WB Predicted band size:

54 kDa

WB Positive control:

U2OS, CEM, K562 and Hela cell lysates

WB Recommended dilution:

1000-5000