兔抗CNOT7多克隆抗體

Background:

The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and X.

Applications:

ELISA, IHC

Name of antibody:

CNOT7

Immunogen:

Fusion protein of human CNOT7

Full name:

CCR4-NOT transcription complex subunit 7

Synonyms:

CAF1; CAF-1; Caf1a; hCAF-1

SwissProt:

Q9UIV1

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human lung cancer

IHC Recommend dilution:

50-100