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  • PAK6抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號 : TW16995
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存:40
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中文名稱: PAK6抗原(重組蛋白)

英文名稱: PAK6 Antigen (Recombinant Protein)

別      名: PAK5

儲      存: 冷凍(-20℃)

相關(guān)類別: 抗原

概述

Fusion protein corresponding to a region derived from 407-658 amino acids of human PAK6

技術(shù)規(guī)格

Full name:

p21 protein (Cdc42/Rac)-activated kinase 6

Synonyms:

PAK5

Swissprot:

Q9NQU5

Gene Accession:

BC035596

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants.