兔抗DCX多克隆抗體

Background:

This gene encodes a member of the doublecortin family. The protein encoded by this gene is a cytoplasmic protein and contains two doublecortin domains, which bind microtubules. In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The encoded protein appears to direct neuronal migration by regulating the organization and stability of microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex.

Applications:

ELISA, WB, IHC

Name of antibody:

DCX

Immunogen:

Synthetic peptide of human DCX

Full name:

doublecortin

Synonyms：

DC; DBCN; LISX; SCLH; XLIS

SwissProt:

O43602

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer and human esophagus cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

49 kDa

WB Positive control:

Human fetal brain tissue and 293T，K562，Jurkat cell

WB Recommended dilution:

500-2000