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  • PTRH2 抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW17637
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存:75
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中文名稱(chēng):  PTRH2 抗原(重組蛋白)

英文名稱(chēng): PTRH2 Antigen (Recombinant Protein)

別      名: peptidyl-tRNA hydrolase 2; BIT1; PTH2; CFAP37; CGI-147

儲(chǔ)      存:  冷凍(-20℃)

相關(guān)類(lèi)別: 抗原

概述

Fusion protein corresponding to a region derived from 63-179 amino acids of human PTRH2


技術(shù)規(guī)格

Full name:

peptidyl-tRNA hydrolase 2

Synonyms:

BIT1; PTH2; CFAP37; CGI-147

Swissprot:

Q9Y3E5

Gene Accession:

BC006807

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

PTRH2 (peptidyl-tRNA hydrolase 2), also known as BIT1 (Bcl-2 inhibitor of transcription 1), is a 179 amino acid mitochondrial protein. During apoptosis, PTRH2 is released from the mitochondia to the cytoplasm. Once in the cytoplasm, PTRH2 regulates the function of two transcriptional regulators, TLE5 and TLE1, thereby promoting caspase-independent cell death. It is also believed that the natural substrate for PTRH2 may be petidyl-tRNAs, which leave the ribosomes during protein synthesis.