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  • TLR5抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW17767
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存:90
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中文名稱:TLR5抗原(重組蛋白)

英文名稱 TLR5 Antigen (Recombinant Protein)

別      名: TIL3; SLEB1

儲(chǔ)      存: 冷凍(-20℃)

相關(guān)類別: 抗原

概  述:

Fusion protein corresponding to a region derived from 3-180 amino acids of human TLR5


技術(shù)規(guī)格:

Full name:

toll-like receptor 5

Synonyms:

TIL3; SLEB1

Swissprot:

O60602

Gene Accession:

BC109119

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.