中文名稱:IL1RAP抗原(重組蛋白)
英文名稱: IL1RAP Antigen (Recombinant Protein)
儲 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概述
Fusion protein corresponding to a region derived from 22-356 amino acids of human IL1RAP |
Full name: |
Interleukin-1 receptor accessory protein |
Synonyms: |
IL1R3, C3orf13, IL-1RAcP |
Swissprot: |
Q9NPH3 |
Gene Accession: |
BC053621 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Interleukin 1 induces synthesis of acute phase and proinflammatory proteins during infection, tissue damage, or stress, by forming a complex at the cell membrane with an interleukin 1 receptor and an accessory protein. This gene encodes the interleukin 1 receptor accessory protein. The protein is a necessary part of the interleukin 1 receptor complex which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in two transcript variants encoding two different isoforms, one membrane-bound and one soluble. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress. |