Background: |
This gene encodes one of the three enolase isoenzymes found in mammals. This isoenzyme, a homodimer, is found in mature neurons and cells of neuronal origin. A switch from alpha enolase to gamma enolase occurs in neural tissue during development in rats and primates. Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival. |
Applications: |
ELISA, WB |
Name of antibody: |
ENO2 |
Immunogen: |
Synthetic peptide of human ENO2 |
Full name: |
Enolase 2 (gamma, neuronal) |
Synonyms: |
NSE |
SwissProt: |
P09104 |
ELISA Recommended dilution: |
2000-10000 |
WB Predicted band size: |
47 kDa |
WB Positive control: |
293T and Jurkat cells |
WB Recommended dilution: |
1000-5000 |