購(gòu)物車
幫助
021-54845833/15800441009
中文名稱：兔抗CCND1多克隆抗體
英文名稱： Anti-CCND1 rabbit polyclonal antibody
別 名： BCL1, PRAD1, U21B31, D11S287E
儲(chǔ) 存： 冷凍（-20℃）
抗 原： CCND1
宿 主： Rabbit
相關(guān)類別： 一抗
反應(yīng)種屬： Human, Mouse, Rat
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
CCND1 |
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Immunogen: |
Synthetic peptide of human CCND1 |
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Full name: |
Cyclin D1 |
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Synonyms： |
BCL1, PRAD1, U21B31, D11S287E |
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SwissProt: |
P24385 |
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ELISA Recommended dilution: |
500-5000 |
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IHC positive control: |
Human breast cancer and Human thyroid cancer |
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IHC Recommend dilution: |
10-50 |
