中文名稱: PARP11抗原(重組蛋白)
相關(guān)類別: 抗原
概 述
Full name: |
poly (ADP-ribose) polymerase family, member 11 |
Synonyms: |
ARTD11; MIB006; C12orf6 |
Swissprot: |
Q9NR21 |
Gene Accession: |
BC017569 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Poly(ADP-ribosylation) is a method of DNA damage-dependent posttranslational modification that helps to rescue injured proliferating cells from cell death. The PARP (poly(ADP-ribose) polymerase) proteins comprise a superfamily of enzymes that functionally modify histones and other nuclear proteins, thereby preventing cell death. PARPs use NAD+ as a substrate to catalytically transfer ADP-ribose residues onto protein acceptors; a process that, when repeated multiple times, leads to the formation of poly(ADPribose) chains on the protein. |