中文名稱: UTP4 抗原(重組蛋白)
英文名稱: UTP4 Antigen (Recombinant Protein)
別 名: UTP4, small subunit processome component; NAIC; CIRH1A; CIRHIN; TEX292
儲 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述
Full name: |
UTP4, small subunit processome component |
Synonyms: |
NAIC; CIRH1A; CIRHIN; TEX292 |
Swissprot: |
Q969X6 |
Gene Accession: |
BC009348 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a WD40-repeat-containing protein that is localized to the nucleolus. Mutation of this gene causes North American Indian childhood cirrhosis, a severe intrahepatic cholestasis that results in transient neonatal jaundice, and progresses to periportal fibrosis and cirrhosis in childhood and adolescence. Alternative splicing results in multiple transcript variants. |