兔抗EVPL多克隆抗體

Background:

This gene encodes a member of the plakin family of proteins that forms a component of desmosomes and the epidermal cornified envelope. This gene is located in the tylosis oesophageal cancer locus on chromosome 17q25, and its deletion is associated with both familial and sporadic forms of oesophageal squamous cell carcinoma. Patients suffering from the autoimmune mucocutaneous disorder, paraneoplastic pemphigus, develop antibodies against the encoded protein.

Applications:

ELISA, IHC

Name of antibody:

EVPL

Immunogen:

Synthetic peptide of human EVPL

Full name:

envoplakin

Synonyms:

EVPK

SwissProt:

Q92817

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

25-100