兔抗MXD4多克隆抗體

Background:

This gene is a member of the MAD gene family . The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues.

Applications:

IHC

Name of antibody:

MXD4

Immunogen:

Synthesized peptide derived from internal of human MAD4.

Full name:

MAX dimerization protein 4

Synonyms：

MAD4; MST149; MSTP149; bHLHc12

SwissProt:

Q14582

IHC positive control:

Human brain tissue

IHC Recommend dilution:

50-100