中文名稱: 兔抗NPC1多克隆抗體
英文名稱: Anti-NPC1 rabbit polyclonal antibody
別 名: NPC
相關類別: 一抗
儲 存: 冷凍(-20℃)
宿 主: Rabbit
抗 原: NPC1
反應種屬: Human
標 記 物: Unconjugate
克隆類型 : rabbit polyclonal
技術規(guī)格
Background: |
This gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain. It is predicted to have a cytoplasmic C-terminus, 13 transmembrane domains, and 3 large loops in the lumen of the endosome - the last loop being at the N-terminus. This protein transports low-density lipoproteins to late endosomal/lysosomal compartments where they are hydrolized and released as free cholesterol. |
Applications: |
ELISA, IHC |
Name of antibody: |
NPC1 |
Immunogen: |
Synthetic peptide of human NPC1 |
Full name: |
Niemann-Pick disease, type C1 |
Synonyms: |
NPC |
SwissProt: |
O15118 |
ELISA Recommended dilution: |
1000-2000 |
IHC positive control: |
Human liver cancer |
IHC Recommend dilution: |
25-100 |