Background: |
This gene encodes an evolutionarily-conserved protein containing an N-terminal chromodomain and a C-terminal SET domain. The encoded protein is a histone methyltransferase that trimethylates lysine 9 of histone H3, which results in transcriptional gene silencing. Loss of function of this gene disrupts heterochromatin formation and may cause chromosome instability. Alternative splicing results in multiple transcript variants. |
Applications: |
ELISA, WB |
Name of antibody: |
SUV39H1 |
Immunogen: |
Fusion protein of human SUV39H1 |
Full name: |
suppressor of variegation 3-9 homolog 1 |
Synonyms: |
MG44; KMT1A; SUV39H; H3-K9-HMTase 1 |
SwissProt: |
O43463 |
ELISA Recommended dilution: |
5000-10000 |
WB Predicted band size: |
48 kDa |
WB Positive control: |
Hela, Raji and HepG2 cell lysates |
WB Recommended dilution: |
500-2000 |