中文名稱: 兔抗WEE2多克隆抗體
英文名稱: Anti-WEE2 rabbit polyclonal antibody
別 名: WEE1B
相關類別:一抗
儲 存: 冷凍(-20℃)
宿 主: Rabbit
抗 原: WEE2
反應種屬: Human
標 記 物: Unconjugate
克隆類型: rabbit polyclonal
技術規(guī)格
Background: |
Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1/CDC2 and acts as a key regulator of meiosis during both prophase I and metaphase II (PubMed:29606300). Required to maintain meiotic arrest in oocytes during the germinal vesicle (GV) stage, a long period of quiescence at dictyate prophase I, by phosphorylating CDK1 at 'Tyr-15', leading to inhibit CDK1 activity and prevent meiotic reentry. Also required for metaphase II exit during egg activation by phosphorylating CDK1 at 'Tyr-15', to ensure exit from meiosis in oocytes and promote pronuclear formation (By similarity). |
Applications: |
ELISA, IHC |
Name of antibody: |
WEE2 |
Immunogen: |
Synthetic peptide of human WEE2 |
Full name: |
WEE1 homolog 2 |
Synonyms: |
OOMD5; WEE1B |
SwissProt: |
P0C1S8 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human liver cancer and Human colorectal cancer |
IHC Recommend dilution: |
25-100 |