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    • 品牌 : 通蔚生物
    • 目錄號 : TW4475
    • 應用 : 僅限于科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
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中文名稱: 兔抗WEE2多克隆抗體

英文名稱:
Anti-WEE2 rabbit polyclonal antibody

別       名:
WEE1B

相關類別:一抗

儲       存:
冷凍(-20℃)

宿       主:
Rabbit

抗       原:
WEE2

反應種屬:
Human

標 記  物:
Unconjugate

克隆類型:
rabbit polyclonal

技術規(guī)格

Background:

Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1/CDC2 and acts as a key regulator of meiosis during both prophase I and metaphase II (PubMed:29606300). Required to maintain meiotic arrest in oocytes during the germinal vesicle (GV) stage, a long period of quiescence at dictyate prophase I, by phosphorylating CDK1 at 'Tyr-15', leading to inhibit CDK1 activity and prevent meiotic reentry. Also required for metaphase II exit during egg activation by phosphorylating CDK1 at 'Tyr-15', to ensure exit from meiosis in oocytes and promote pronuclear formation (By similarity).

Applications:

ELISA, IHC

Name of antibody:

WEE2

Immunogen:

Synthetic peptide of human WEE2

Full name:

WEE1 homolog 2

Synonyms:

OOMD5; WEE1B

SwissProt:

P0C1S8

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer and Human colorectal cancer

IHC Recommend dilution:

25-100