購(gòu)物車(chē)
幫助
021-54845833/15800441009
中文名稱(chēng)：兔抗WT1多克隆抗體
英文名稱(chēng)： Anti-WT1 rabbit polyclonal antibody
別 名： GUD; AWT1; WAGR; WT33;NPHS4; WIT-2; EWS-WT1
相關(guān)類(lèi)別： 一抗
儲(chǔ) 存： 冷凍（-20℃） 避光
宿 主： Rabbit
標(biāo) 記 物： Unconjugate
克隆類(lèi)型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm's tumors. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation site upstream of and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated. |
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Applications: |
WB |
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Name of antibody: |
WT1 |
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Immunogen: |
Fusion protein of human WT1 |
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Full name: |
Wilms tumor 1 |
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Synonyms： |
GUD; AWT1; WAGR; WT33;NPHS4; WIT-2; EWS-WT1 |
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SwissProt: |
P19544 |
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WB Predicted band size: |
49 kDa |
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WB Positive control: |
Kidney tissue |
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WB Recommended dilution: |
500-2000 |
