兔抗CDC42BPA多克隆抗體

Background:

The protein encoded by this gene is a member of the Serine/Threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described, and the full-length nature of two of them has been reported.

Applications:

WB

Name of antibody:

CDC42BPA

Immunogen:

Synthesized peptide derived from Internal of human MRCKa.

Full name:

CDC42 binding protein kinase alpha (DMPK-like)

Synonyms：

MRCK; MRCKA; PK428

SwissProt:

Q5VT25

WB Predicted band size:

197 kDa

WB Positive control:

Jurkat and COLO205 lysates

WB Recommended dilution:

500-3000