小鼠抗ARHGEF18單克隆抗體

Background:

Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GFE family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain. Alternatively spliced transcript variants encoding different isoforms have been identified.

Applications:

WB

Name of antibody:

ARHGEF18

Immunogen:

Fusion protein of human ARHGEF18

Full name:

Rho/Rac guanine nucleotide exchange factor 18

Synonyms:

RP78; P114-RhoGEF

SwissProt:

Q6ZSZ5

WB Predicted band size:

131 KD

WB Positive control:

293T, A431, Hela, HepG2 cell lysates

WB Recommended dilution:

500-2000