小鼠抗BCL2單克隆抗體

Background:

This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends. [provided by RefSeq, Jul 2008].

Applications:

WB, IHC

Name of antibody:

BCL2

Immunogen:

Fusion protein of human BCL2

Full name:

B-cell CLL/lymphoma 2 (BCL2), transcript variant alpha

Synonyms:

Bcl-2; PPP1R50

SwissProt:

P10415

IHC positive control:

human lymphoma tissue and human tonsil tissue

IHC Recommend dilution:

30-150

WB Predicted band size:

26 kDa

WB Positive control:

HepG2, Hela, A549, Jurkat, MDCK, PC12 and MCF7 cell lysates

WB Recommended dilution:

500-2000