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  • ZKSCAN3 抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW6678
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存:20
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中文名稱(chēng): ZKSCAN3 抗原(重組蛋白)

英文名稱(chēng): ZKSCAN3 Antigen (Recombinant Protein)

別     名: zinc finger with KRAB and SCAN domains 3; ZF47; Zfp47; ZFP306; ZNF306; ZNF309; zfp-47; ZSCAN13; ZSCAN35; dJ874C20.1; dJ874C20.1.

相關(guān)類(lèi)別: 抗原

儲(chǔ)     存: 冷凍(-20℃)

概     述

Fusion protein corresponding to a region derived from 339-538 amino acids of human ZKSCAN3

技術(shù)規(guī)格

Full name:

zinc finger with KRAB and SCAN domains 3

Synonyms:

ZF47; Zfp47; ZFP306; ZNF306; ZNF309; zfp-47; ZSCAN13; ZSCAN35; dJ874C20.1; dJ874C20.1.

Swissprot:

Q9BRR0

Gene Accession:

BC006118

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migation in various tumors and myelomas.