中文名稱(chēng):小鼠抗IL18BP單克隆抗體
Background: |
The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
Applications: |
WB |
Name of antibody: |
IL18BP |
Immunogen: |
Fusion protein of human IL18BP |
Full name: |
interleukin 18 binding protein |
Synonyms: |
IL18BPa |
SwissProt: |
O95998 |
WB Predicted band size: |
21 kDa |
WB Positive control: |
K562 cell, CHO-K1 cell, CHO-K1 cells transfected by IL18BP-PDGFR fusion protein cell lysates |
WB Recommended dilution: |
200-1000 |