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  • 兔抗HIRA多克隆抗體

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    • 品牌 : 通蔚生物
    • 目錄號 : TW7700
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存:20
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中文名稱: 兔抗HIRA多克隆抗體

英文名稱: Anti-HIRA rabbit polyclonal antibody

別     名: TUP1; DGCR1; TUPLE1

相關(guān)類別: 一抗

儲     存: 冷凍(-20℃)

宿     主: Rabbit

抗     原: HIRA
反應(yīng)種屬: Human, Mouse

標(biāo) 記 物: Unconjugate

克隆類型: rabbit polyclonal

技術(shù)規(guī)格

Background:

This gene encodes a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this gene in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. This gene plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development.

Applications:

ELISA, IHC

Name of antibody:

HIRA

Immunogen:

Synthetic peptide of human HIRA

Full name:

histone cell cycle regulator

Synonyms:

TUP1; DGCR1; TUPLE1

SwissProt:

P54198

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human brain

IHC Recommend dilution:

20-100