兔抗ALDH7A1多克隆抗體

Background:

The protein encoded by this gene is a member of subfamily 7 in the aldehyde dehydrogenase gene family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This particular member has homology to a previously described protein from the green garden pea, the 26g pea turgor protein. It is also involved in lysine catabolism that is known to occur in the mitochondrial matrix. Recent reports show that this protein is found both in the cytosol and the mitochondria, and the two forms likely arise from the use of alternative translation initiation sites. An additional variant encoding a different isoform has also been found for this gene. Mutations in this gene are associated with pyridoxine-dependent epilepsy. Several related pseudogenes have also been identified.

Applications:

ELISA, WB, IHC

Name of antibody:

ALDH7A1

Immunogen:

Synthetic peptide of human ALDH7A1

Full name:

aldehyde dehydrogenase 7 family member A1

Synonyms:

EPD; PDE; ATQ1

SwissProt:

P49419

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer

IHC Recommend dilution:

20-100

WB Predicted band size:

59 kDa

WB Positive control:

Human fetal liver tissue and Human liver tissue, Hela, HepG2 and A172 cell, Rat liver tissue lysates

WB Recommended dilution:

200-1000