兔抗MPZL1多克隆抗體

Background:

Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role; it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility.

Applications:

ELISA, IHC

Name of antibody:

MPZL1

Immunogen:

Fusion protein of human MPZL1

Full name:

myelin protein zero like 1

Synonyms:

PZR; PZRa; PZRb; PZR1b; MPZL1b

SwissProt:

O95297

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human tonsil and Human brain

IHC Recommend dilution:

20-100