兔抗PRKAA1多克隆抗體

Background:

The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Applications:

ELISA, IHC

Name of antibody:

PRKAA1

Immunogen:

Synthetic peptide of human PRKAA1

Full name:

protein kinase AMP-activated catalytic subunit alpha 1

Synonyms:

AMPK; AMPKa1

SwissProt:

Q13131

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human tonsil and Human esophagus cancer

IHC Recommend dilution:

30-150