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細(xì)胞系

細(xì)胞庫(kù)

基礎(chǔ)培養(yǎng)基

完全培養(yǎng)基

原代細(xì)胞

細(xì)胞專用培養(yǎng)基

菌株

生化試劑

病理染色液

科研抗體

CISH 抗原（重組蛋白）

規(guī)格：

數(shù)量：

購(gòu)買(mǎi)數(shù)量

價(jià)格：￥

中文名稱： CISH 抗原（重組蛋白）

英文名稱： CISH Antigen (Recombinant Protein)

別名： cytokine inducible SH2 containing protein; CIS; G18; SOCS; CIS-1; BACTS2

相關(guān)類別：抗原

儲(chǔ) 存： 冷凍（-20℃）

概述

Fusion protein corresponding to a region derived from 59-258 amino acids of human CISH

技術(shù)規(guī)格

Full name:	cytokine inducible SH2 containing protein
Synonyms:	CIS; G18; SOCS; CIS-1; BACTS2
Swissprot:	Q9NSE2
Gene Accession:	BC031590
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	The protein encoded by this gene contains a SH2 domain and a SOCS box domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by IL2, IL3, GM-CSF and EPO in hematopoietic cells. Proteasome-mediated degradation of this protein has been shown to be involved in the inactivation of the erythropoietin receptor. Multiple transcript variants encoding different isoforms have been found for this gene.

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