兔抗HOXD10多克隆抗體

Background:

This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The encoded nuclear protein functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus (also known as "rocker-bottom foot" deformity or congenital convex pes valgus) and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease.

Applications:

ELISA, WB, IHC

Name of antibody:

HOXD10

Immunogen:

Synthetic peptide of human HOXD10

Full name:

homeobox D10

Synonyms:

HOX4; HOX4D; HOX4E; Hox-4.4

SwissProt:

P28358

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human prostate cancer and human cervical cancer

IHC Recommend dilution:

20-100

WB Predicted band size:

38 kDa

WB Positive control:

Hela cell lysate

WB Recommended dilution:

200-1000