技術規(guī)格
Background: |
May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit |
Applications: |
WB, IHC |
Name of antibody: |
IRS1 (Phospho-Ser639) |
Immunogen: |
Synthetic peptide of human IRS1 (Phospho-Ser639) |
Full name: |
insulin receptor substrate 1 (Phospho-Ser639) |
Synonyms: |
HIRS-1 |
SwissProt: |
P35568 |
IHC positive control: |
Human breast carcinoma |
IHC Recommend dilution: |
50-100 |
WB Predicted band size: |
180 kDa |
WB Positive control: |
293 cells untreated or treated with serum |
WB Recommended dilution: |
500-1000 |