中文名稱:CCNF抗原(重組蛋白)
英文名稱:CCNF Antigen (Recombinant Protein)
儲(chǔ) 存:冷凍(-20℃)
相關(guān)類別:抗原
概述
Fusion protein corresponding to C terminal 300 amino acids of human CCNF |
技術(shù)規(guī)格
Full name: |
cyclin F |
Synonyms: |
FBX1, FBXO1 |
Swissprot: |
P41002 |
Gene Accession: |
BC012349 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a member of the cyclin family. Cyclins are important regulators of cell cycle transitions through their ability to bind and activate cyclin-dependent protein kinases. This member also belongs to the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it was one of the first proteins in which the F-box motif was identified. |